Entries by admin

SiChem congratulates the Nobel Laureates

SiChem congratulates the Nobel Laureates in Chemistry Frances H. Arnold (California Institute of Technology / Caltech), George P. Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). SiChem provides all 3 institutes with its useful tools for biochemical research.

SiChem sponsors the iGEM Team Tübingen, Germany

SiChem supports the Tübingen team at the “international Genetically Engineered Machine” (iGEM) competition. More than 300 teams from all over the world take part in this renowned competition in the field of synthetic biology. They present their results to an international jury in Boston (iGEM).

Rapidly reversible Chemical Dimerizer rCD1 is now available at SiChem

The first rapidly reversible chemical dimerization system – rCD1 – , which permits to determine kinetics of lipid metabolizing enzymes in living cells, is now available at SiChem . This new system was applied to induce and stop the activity of phosphatidyl 3-kinase (PI3K) (SC-7000_Chemical_Dimerizer_info). rCD1 is available in 2 sizes: 100µg (for app. 20 […]

INO-4995 has potential in treatment of Cystic Fibrosis (CF)

INO-4995 (1-O-octyl-2-O-butyryl-D-myo-inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester) is an ion channel modulator that is slowly metabolized in cells. Studies have shown that it inhibits ENaC activity while promoting expression of the calcium-activated chloride channel, TMEM16a, in membranes. Thus it has potential therapeutic activity in the treatment of cystic fibrosis where it normalized nasal potential difference (npd) in a […]

SiChem – member of the i3 – Life Sciences Cluster – is a ” Landmark in the Land of Ideas”

The competition ” 100 Landmarks in the Land of Ideas” promotes ideas for urgent issues of tomorrow. The i3 – Life Sciences Cluster tries to find answers to the increasing life expectancy and the associated diseases. Innovative diagnostic companies in the Bremen / Bremerhaven region have joined forces to investigate biomarkers that may indicate certain […]