Together with our cooperation partners from Mannheim University of Applied Sciences (HSM), we developed a completely new concept for vacuum-stable MALDI matrices.
Now it’s published in “Angewandte Chemie”
The trick is: we combined standard MALDI matrices with a caging group – this increases the vacuum stability. The caged group is then cleaved by the MALDI laser.
The vacuumstable MALDI-matrices are available at SiChem’s webshop: caged MALDI-Matrices
MSI (mouse brain) with vacuumstable MALDI-matrix measured after 0h and 72h