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The aim of the project is the development of a new process for targeted and position-specific immobilization of enzymes on carrier materials. The immobilization of enzymes increases their stability and the possibility of reusability and allows catalytic steps to run more effectively and with higher turnover. The project will run for 36 months and has […]
SiChem congratulates the Nobel Laureates in Chemistry Frances H. Arnold (California Institute of Technology / Caltech), George P. Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). SiChem provides all 3 institutes with its useful tools for biochemical research.
SiChem sponsors with pre4U this year’s SPICA – the 17th International Symposium for Preparative and Industrial Chromatography.
The first rapidly reversible chemical dimerization system – rCD1 – , which permits to determine kinetics of lipid metabolizing enzymes in living cells, is now available at SiChem . This new system was applied to induce and stop the activity of phosphatidyl 3-kinase (PI3K) (SC-7000_Chemical_Dimerizer_info). rCD1 is available in 2 sizes: 100µg (for app. 20 […]
INO-4995 (1-O-octyl-2-O-butyryl-D-myo-inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester) is an ion channel modulator that is slowly metabolized in cells. Studies have shown that it inhibits ENaC activity while promoting expression of the calcium-activated chloride channel, TMEM16a, in membranes. Thus it has potential therapeutic activity in the treatment of cystic fibrosis where it normalized nasal potential difference (npd) in a […]
The competition ” 100 Landmarks in the Land of Ideas” promotes ideas for urgent issues of tomorrow. The i3 – Life Sciences Cluster tries to find answers to the increasing life expectancy and the associated diseases. Innovative diagnostic companies in the Bremen / Bremerhaven region have joined forces to investigate biomarkers that may indicate certain […]
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