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Dear customers and partners, we are all part of a complex supply chain in a globalized world, with all its advantages and disadvantages. We are currently experiencing the rapid global spread of COVID-19 and would like to take responsibility as a supplier: most importantly, SiChem has taken all necessary preventive measures, e.g. home office where […]
The conference will take place from 12th to 15th of December at the Oregeon Health and Science University (OHSU) in Portland, USA. This biennial international conference focuses on the growing intersection of chemical biology and physiology. This exciting field offers innovative opportunities for the development of drug targets and therapy concepts. Leading scientists from all […]
We will be at the CPhI in Frankfurt on November 6th and we still have available dates – if you like to meet us, just send us an e-mail and let us know when you will be available (info@sichem.de).
From Monday 21st to Tuesday 22nd October 2019 the Symposium of Noncanonical amino acids – Tools for biological and biophysical investigations will be held in Paris. It is co-organized with the French Peptides and Proteins Group (GFPP) This international symposium will focus on the emergent use of noncanonical amino acids (ncAAs) in peptide and protein science. […]
The trend in MALDI analysis today is towards large sample quantities, long scanning times and locally accurate measurement resolution. However, today’s MALDI matrices limit this progress for two reasons: First, they are not vacuum stable. As a result, the layer thickness changes during the time of a MALDI scan. This results in a loss of […]
The aim of the project is the development of a new process for targeted and position-specific immobilization of enzymes on carrier materials. The immobilization of enzymes increases their stability and the possibility of reusability and allows catalytic steps to run more effectively and with higher turnover. The project will run for 36 months and has […]
SiChem congratulates the Nobel Laureates in Chemistry Frances H. Arnold (California Institute of Technology / Caltech), George P. Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). SiChem provides all 3 institutes with its useful tools for biochemical research.
SiChem sponsors with pre4U this year’s SPICA – the 17th International Symposium for Preparative and Industrial Chromatography.
The first rapidly reversible chemical dimerization system – rCD1 – , which permits to determine kinetics of lipid metabolizing enzymes in living cells, is now available at SiChem . This new system was applied to induce and stop the activity of phosphatidyl 3-kinase (PI3K) (SC-7000_Chemical_Dimerizer_info). rCD1 is available in 2 sizes: 100µg (for app. 20 […]
INO-4995 (1-O-octyl-2-O-butyryl-D-myo-inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester) is an ion channel modulator that is slowly metabolized in cells. Studies have shown that it inhibits ENaC activity while promoting expression of the calcium-activated chloride channel, TMEM16a, in membranes. Thus it has potential therapeutic activity in the treatment of cystic fibrosis where it normalized nasal potential difference (npd) in a […]
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