Publikationen

2018

Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita.

Yu X, Akbarzadeh R, Pieper M, Scholzen T, Gehrig S, Schultz C, Zillikens D, König P, Petersen F.(2018)
J Invest Dermatol doi: 10.1016/j.jid.2018.03.1499
Europe PMC | doi

Novel lipid tools and probes for biological investigations.

Laguerre A, Schultz C. (2018)
Elife 6 doi: 10.7554/eLife.30203
Curr. Opin. Cell Biol. 53:97-104. doi: 10.1016/j.ceb.2018.06.013
Europe PMC | doi

A Bifunctional Noncanonical Amino Acid: Synthesis, Expression, and Residue-Specific Proteome-wide Incorporation.

Hoffmann JE, Dziuba D, Stein F, Schultz C. (2018)
Biochemistry 57(31) doi: 10.1021/acs.biochem.8b00397
Europe PMC | doi

Endogenous Fatty Acids are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion.

Hauke S, Keutler K, Phapale P, Yushchenko DA, Schultz C. (2018)

Diabetes doi: 10.2337/db17-1215
Europe PMC | doi

PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules.

Kath C, Goni-Oliver P, Müller R, Schultz C, Haucke V, Eickholt B, Schmoranzer J. (2018)
PLoS One 13(4) doi: 10.1371/journal.pone.0193257
Europe PMC | doi

Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis.

Dittrich AS, Kühbandner I, Gehrig S, Rickert-Zacharias V, Twigg M, Wege S, Taggart CC, Herth F, Schultz C, Mall MA. (2018)

Eur Respir J 51(3) doi: 10.1183/13993003.01910-2017
Europe PMC | doi

2017

Optical control of GPR40 signalling in pancreatic beta-cells

Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. (2017)
CHEM SCI 8:7604-7610. doi: 10.1039/c7sc01475a
doi

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.

Walter AM, Müller R, Tawfik B, Wierda KD, Pinheiro PS, Nadler A, McCarthy AW, Ziomkiewicz I, Kruse M, Reither G, Rettig J, Lehmann M, Haucke V, Hille B, Schultz C, Sorensen JB. (2017)
Elife 6 doi: 10.7554/eLife.30203
Europe PMC | doi

Local Generation and Imaging of Hydrogen Peroxide in Living Cells.

Bogdanova YA, Schultz C, Belousov VV. (2017)
Curr Protoc Chem Biol 9(2):117-127. doi: 10.1002/cpch.20
Europe PMC | doi

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

Marat AL, Wallroth A, Lo WT, Müller R, Norata GD, Falasca M, Schultz C, Haucke V. (2017)
Science 356(6341):968-972. doi: 10.1126/science.aaf8310
Europe PMC | doi

Tetraspanin microdomains control localized protein kinase C signaling in B cells.

Zuidscherwoude M, Dunlock VE, van den Bogaart G, van Deventer SJ, van der Schaaf A, van Oostrum J, Goedhart J, In ‚t Hout J, Hämmerling GJ, Tanaka S, Nadler A, Schultz C, Wright MD, Adjobo-Hermans MJW, van Spriel AB. (2017)
Sci Signal 10(478):1-15. doi: 10.1126/scisignal.aag2755
Europe PMC | doi

A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells.

Schifferer M, Yushchenko DA, Stein F, Bolbat A, Schultz C. (2017)
Cell Chem Biol 525-531. doi: 10.1016/j.chembiol.2017.03.001
Europe PMC | doi

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A. (2017)
Dev. Cell 40(4):331-341. doi: 10.1016/j.devcel.2017.01.015
Europe PMC | doi

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.

Höglinger D, Nadler A, Haberkant P, Kirkpatrick J, Schifferer M, Stein F, Hauke S, Porter FD, Schultz C. (2017)
Proc. Natl. Acad. Sci. U.S.A. 114(7):1566-1571. doi: 10.1073/pnas.1611096114
Europe PMC | doi

Endosomal Phosphatidylinositol-3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses.

Papadopoulos T, Rhee HJ, Subramanian D, Paraskevopoulou F, Mueller R, Schultz C, Brose N, Rhee JS, Betz H. (2017)
J. Biol. Chem. 292(4):1160-1177. doi: 10.1074/jbc.M116.771592
Europe PMC | doi

Reversible Chemical Dimerization by rCD1.

Schifferer M, Feng S, Stein F, Schultz C. (2017)
Meth. Enzymol. 583:173-195. doi: 10.1016/bs.mie.2016.10.035
Europe PMC | doi // this product could be interesting for you: SC-7000

2016

Yeast three-hybrid-Targetidentifizierung per Klick-Chemie

Stefano Rizzo, Rene Lang, Jacqueline Franke, Miriam Rittner
BIOSpektrum November 2016, Volume 22, Issue 7, pp 734–735. DOI: 10.1007/s12268-016-0752-6. http://rdcu.be/mCpy

Recent developments of genetically encoded optical sensors for cell biology.

Bolbat A, Schultz C. (2016)
Biol. Cell doi: 10.1111/boc.201600040
Europe PMC | doi

A Protease Inhibitor Tackles Epithelial Sodium Channels in Cystic Fibrosis.

Rickert-Zacharias V, Schultz C, Mall MA. (2016)
Am. J. Respir. Crit. Care Med. 194(6):650-652. doi: 10.1164/rccm.201604-0781ed

Europe PMC | doi

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.

Bilgin M, Born P, Fezza F, Heimes M, Mastrangelo N, Wagner N, Schultz C, Maccarrone M, Eaton S, Nadler A, Wilm M, Shevchenko A. (2016)
Sci Rep 6:27920. doi: 10.1038/srep27920
Europe PMC | doi

Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.

Hövelmann F, Kedziora KM, Nadler A, Müller R, Jalink K, Schultz C. (2016)
Cell Chem Biol doi: 10.1016/j.chembiol.2015.11.019

Europe PMC | doi

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B. (2016)
PLoS ONE 11(4) doi: 10.1371/journal.pone.0153009

Europe PMC | doi

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

Samarin J, Laketa V, Malz M, Roessler S, Stein I, Horwitz E, Singer S, Dimou E, Cigliano A, Bissinger M, Falk CS, Chen X, Dooley S, Pikarsky E, Calvisi DF, Schultz C, Schirmacher P, Breuhahn K. (2016)
Hepatology 63(3):813-826. doi: 10.1002/hep.28357

Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo.

Pavlovic I, Thakor DT, Vargas JR, McKinlay CJ, Hauke S, Anstaett P, Camuña RC, Bigler L, Gasser G, Schultz C, Wender PA, Jessen HJ. (2016)
Nat Commun 7 doi: 10.1038/ncomms10622

A phosphoinositide conversion mechanism for exit from endosomes

Katharina Ketel, Michael Krauss, Anne-Sophie Nicot, Dmytro Puchkov, Marnix Wieffer, Rainer Müller, Devaraj Subramanian, Carsten Schultz, Jocelyn Laporte& Volker Haucke
Nature 529, 408–412 (21 January 2016); doi:10.1038/nature16516

2015

Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling

Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C.
Chem-Eur J 21(35):12266-12270. doi:10.1002/chem.201501647 these products could be interesting for you: SC-8008 (TCO*A)

Frontispiece: Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.

Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C.
Chemistry 21(35) doi:10.1002/chem.201583561

A single-cell model of PIP3 dynamics using chemical dimerization

MacNamara A, Stein F, Feng S, Schultz C, Saez-Rodriguez J.
Bioorg. Med. Chem. 2015, 23(12): 2868 / doi:10.1016/j.bmc.2015.04.074

Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane

Schifferer M, Feng S, Stein F, Tischer C, Schultz C.
Bioorg. Med. Chem. 2015, 23 (12): 2862 / doi:10.1016/j.bmc.2015.03.048

Loss of atomic nitrogen from even-electron ions? A study on benzodiazepines

Axel Treu, Miriam Rittner, Dorit Kemken, Hans-Martin Schiebel, Peter Spiteller and Thomas Dülcks
J. Mass Spectrom. 2015, 50, 978–986

Covalent Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides - Total synthesis of seragamide A

H.-D. Arndt, S. Rizzo, C. Nöcker, V. N. Wakchaure, L.-G. Milroy, V. Bieker, A. Calderon, T. T. N. Tran, S. Brand, L. Dehmelt, H. Waldmann
Chem. Eur. J. 2015, accepted