Click Chemistry

Inositol phosphates

Custom Synthesis

made by SiChem

Custom synthesis and Lifescience tools

Sirius Fine Chemicals SiChem GmbH synthesizes APIs for early stage (Toxicology) drug design. A special field of expertise is the preparation of biologically and pharmacologically active compounds with increased bioavailability (prodrugs).

We are one of the leading providers for inositol phosphates as well as a large variety of membranepermeant and photoactivatable derivatives. Our portfolio has been supplemented by clickable unnatural amino acids and other useful tools for Click-Chemistry.

NEW: tools with PEG-linkers: here you will find a large selection of tools with different length PEG-linkers. These are suitable for click-chemistry-reactions or for biotin- and fluorescence- labelling.

Click-Photocrosslinking compounds

Click-Photocrosslinking compounds for photo-affinity labeling (PAL)

 

NEmo: New FRET-based reporter system that detects NE activity – now available at Sichem

Rapidly reversible Chemical Dimerizer rCD1 is now available at SiChem

SiChem congratulates this year’s Nobel Prize winners in Chemistry

Carolyn Bertozzi (Stanford University) Morten Meldal (University of Copenhagen) Barry Sharpless (Scripps Research Institute) This year, the Nobel Prize in Chemistry was awarded to Carolyn Bertozzi of the University of Stanford,…

SiChem sponsors the “Translational Bioimaging RVZ Symposium” in Würzburg (18-20th of September 2022)

In Würzburg, experienced scientists and young researchers from all over the world come together to discuss the state of the art regarding the use of genetic modifications (e.g. genetic code expansion) for future biomedical treatments. The…

TCO-active ester as drug-delivery system

Milan Vrabel et al. believe that performing abiotic chemical reactions within particular organelles at the subcellular level opens up new avenues: by manipulating biological processes in a targeted manner, they can be studied in more detail…