TCO-active ester as drug-delivery system
NewsMilan Vrabel et al. believe that performing abiotic chemical reactions within particular organelles at the subcellular level opens up new avenues: by manipulating biological processes in a targeted manner, they can be studied in more detail…
TCO* for single-molecule super-resolution imaging
NewsGerti Beliu et al. from the University of Würzburg use SiChem's unnatural amino acid Trans-Cyclooct-2-en-L-Lysine (TCO*A; SC-8008 labelled with tetrazine dyes) for dSTORM experiments. A complete labelling and imaging pipeline has been developed…
NEmo explains unexplained phenomenon
NewsNeutrophils are often made responsible for killing bacteria in chronic diseases such as cystic fibrosis (CF). Here, however, there is an unexplained phenomenon: although neutrophils are massively present, long-lasting bacterial infections occur…
BCN-PEG-NHS / TCO-PEG-NHS for bioimaging
NewsFluorescent probes that react with complementary bioorthogonal reagents and subsequently light up are excellent tools for bioimaging applications.
Vrabel et al. have synthesized a series of diverse coumarin-tetrazine probes that can react…
SiChem is one of the TOP10 biotech companies in Bremen
NewsBremen is rather known as a trading city - less as a high-tech location for internationally operating biotech companies. But there are quite a few innovative, research-based companies that offer their products and services worldwide. Some of…
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