From Monday 21st to Tuesday 22nd October 2019 the Symposium of  Noncanonical amino acids – Tools for biological and biophysical investigations will be held in Paris. It is co-organized with the French Peptides and Proteins Group (GFPP)

This international symposium will focus on the emergent use of noncanonical amino acids (ncAAs) in peptide and protein science. It will bring together chemists, biochemists, biologists and biophysicists involved in the development of new technologies using ncAAs and in their application to biological questions.

SiChem offers a number of ncAAs for different experiments. Here you will find a selection of ncAAs

The trend in MALDI analysis today is towards large sample quantities, long scanning times and locally accurate measurement resolution. However, today’s MALDI matrices limit this progress for two reasons:
First, they are not vacuum stable. As a result, the layer thickness changes during the time of a MALDI scan. This results in a loss of sensitivity, a signal drift and thus considerable measurement errors.
Second: Co-crystals with HCCA, 2.5-DHAP or 2.5-DHB usually exceed the size of 10µm, which is why higher resolutions are not possible.

The aim of the project is the development of new vacuum-stable matrices, which form homogeneous co-crystal layer thicknesses over 24h with possible analytes such as peptides, proteins, lipids and active substances.

The aim of the project is the development of a new process for targeted and position-specific immobilization of enzymes on carrier materials. The immobilization of enzymes increases their stability and the possibility of reusability and allows catalytic steps to run more effectively and with higher turnover. The project will run for 36 months and has a volume of more than 500TEUR.

SiChem congratulates the Nobel Laureates in Chemistry Frances H. Arnold (California Institute of Technology / Caltech), George P. Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). Smith (University of Missouri), and Gregory Winter (MRC Laboratory of Molecular Biology). SiChem provides all 3 institutes with its useful tools for biochemical research.

SiChem sponsors with pre4U this year’s SPICA – the 17th International Symposium for Preparative and Industrial Chromatography.