BCN-PEG-NHS / TCO-PEG-NHS for bioimaging

Fluorescent probes that react with complementary bioorthogonal reagents and subsequently light up are excellent tools for bioimaging applications.

Vrabel et al. have synthesized a series of diverse coumarin-tetrazine probes that can react with SiChem’s TCOs and BCNs in seconds to act as labels in living cells. (SC-8106 / SC-8406)


Juraj Galeta, et al.: A Systematic Study of Coumarin–Tetrazine Light-Up Probes for Bioorthogonal Fluorescence Imaging

Chem. Eur. J. 2020, 26, 9945 – 9953