Click Chemistry

Inositol phosphates

Custom Synthesis

made by SiChem

Custom synthesis and Lifescience tools

Sirius Fine Chemicals SiChem GmbH synthesises active substances for the early phase/toxicology of drug development, mainly for the pharmaceutical industry.
Our special focus is on prodrugs, i.e. the active ingredient is initially inactive and is only released IN the organism.
This can be done, for example, by  endogenous enzymes.

A new approach is the release of the API (Active Pharmaceutical Ingredient) through a click reaction: here, the clickable inactive API is first transported to the site of action (e.g. to the tumour), where it reacts with a previously injected antibody or biopolymer that is also clickable.

SiChem also offers a wide range of useful tools, such as:

  • Si-CLICK®: click reagents, such as artificial amino acids, active esters, alkoxides, APIs…
  • Si-PEGs: functionalized PEG linkers for click chemistry or also for biotin and fluorescence labeling
  • Si-LIPs: functionalized Lipids and Derivatives
  • Si-DYEs: (clickable) Dyes with or without PEG-Linker (NEW!)
  • Inositol phosphates: free, membranepermeant and/or photoactivatable derivatives

Flash & Click:
powerful Tools for investigating
lipid signaling in live cells

NEmo: New FRET-based reporter system that detects NE activity – now available at Sichem

Direct linking of our products with
relevant publications
– with bioz

SiChem is one of the TOP10 biotech companies in Bremen

Bremen is rather known as a trading city - less as a high-tech location for internationally operating biotech companies. But there are quite a few innovative, research-based companies that offer their products and services worldwide. Some of…

Smart Simulated Moving Bed Chromatography (sSMB)

SiChem receives BMWi grant (ZIM) together with TU Clausthal for developing Smart Simulated Moving Bed Chromatography (sSMB) Personalised medicine is about treating patients as individually as possible. The drugs administered should have an…

COVID-19

Dear customers and partners, we are all part of a complex supply chain in a globalized world, with all its advantages and disadvantages. We are currently experiencing the rapid global spread of COVID-19 and would like to take responsibility…